Stages of Nutritional Vitamin Deficiency

In our days certain typical disease patterns have been shown to be due to vitamin deficiency. It is particular noticed in countries where diets are unbalanced and inadequate, or where there are particular dietary customs. Examples of the most commonly observed diseases are xerophthalmia, rickets, beriberi, pellagra and scurvy, which result from deficiencies of vitamin A, vitamin D, thiamin, niacin and vitamin C, respectively. In meantime deficiency of a single member of the vitamin B group is rare in humans.

As these vitamins are largely found together in nature, and foodstuffs lacking in one member of the complex are likely to be poor in the others. In addition, the obvious manifestations of deficiency of this group overlap to some extent.
Subclinical deficiency and marginal deficiency are synonymous terms used to describe conditions in ipeople who are not clinically nutrient deficient, but who appear to be close to it.
By reference to the sequence of events in the development of vitamin deficiency, scientists emphasized the importance of preventing functional metabolic disturbances that can evolve into overt clinical symptoms. This sequence can be subdivided into six stages as follows.

Stage 1
Body stores of the vitamin are progressively depleted. A decreased vitamin excretion in the urine is often the first symptom. Normal blood levels are maintained by homeostatic mechanisms in the very early stages of deficiency.

Stage 2
The urinary excretion of the vitamin is further decreased and vitamin concentrations in the blood and other tissues are lowered. A diminished concentration of vitamin metabolites might also be observed.

Stage 3
There are changes in biochemical parameters such as low concentrations of the vitamin in blood, urine and tissues, and a low activity of vitamin- dependent enzymes or hormones. Immune response might also be reduced. Non-specific subclinical symptoms such as general malaise, loss of appetite and other mental changes appear.

Stage 4
The biochemical alterations become more severe and morphological or functional disturbances are observed. These disturbances might be corrected by vitamin dosing in therapeutic amounts within a relatively short time or vitamin supplementation in amounts of (or exceeding) the recommended dietary allowances over a longer period. Malformation of cells is reversible at this stage.

Stage 5
The classical clinical symptoms of vitamin deficiency will appear. Anatomical alterations characterizedby reversible damage of tissues might be cured in general by hospitalization of the patient. In most cases there are deficiencies of several nutrients and a complicated dietetic and therapeutic regimen has to be followed.

Stage 6
The morphological and functional disturbances will become irreversible, finally leading to death in extreme cases. From the health point of view, clinical studies have shown that the borderline vitamin deficiency is represented by the transition from the third to the fourth stage.

by materials: Vitamins: Their Role in the Human Body. G.F.M. Ball Consultant, London, UK

Don’t miss symptoms of Vitamin E deficiency

Vitamin E is a group of lipid-soluble compounds- tocopherols and tocotrienols. It is very important in keeping us healthy and young-looking through its action as an antioxidant. Natural sources of vitamin E are vegetable oil, avocado, and nuts. These are essential nutrients because the body cannot produce vitamin E on its own.

Vitamin E deficiency is health a disorder that may be inherited. Being deficient in it means that the body is impaired in absorbing fats that usually carry these fat-loving compounds. Vitamin E deficiency due to poor nutrition is very rare, but still possible, especially in underdeveloped countries. Here are 4 symptoms of vitamin E deficiency:


Anemia can be a symptom of vitamin E deficiency. Anemia is a blood disorder wherein there is a low amount of red blood cells present in the blood. Red blood cells (RBCs) are important element of the blood because through hemoglobin, RBCs transport oxygen to other parts of the body. Oxygen is needed for cellular respiration. Hemolytic anemia is an anemia where red blood cells are abnormally broken down.

In research findings, there was a link with infants who have pronounced low birth weight and vitamin E deficient. This deficiency leads to hemolytic anemia, which, in turn, triggers the degradation of the red blood cells. Administration of doses of vitamin E proved to be helpful in treating these infants. They were treated with tocopherols to help them absorb the vitamin E.

Poor Balance

Vitamin E works as an antioxidant, thus deficiency in this vitamin will result to a series of great oxidative stress by many cells or tissues. This could lead to damage in many parts of the body. This could be observed in people who have vitamin E deficiencies and are suffering from certain neurologic effects of their case. Vitamin E deficiency affects the central nervous system. Thus, a person greatly lacking vitamin E will experience nerve degeneration of the hands and feet, poor reflexes, impaired coordination, and loss of balance.

Muscle Weakness

Another symptom of vitamin E deficiency is myopathy, wherein the muscular fibers do not function well or are weakened. There was even a study involving guinea pigs wherein the combined deficiency in selenium and vitamin E levels resulted to fatal myopathy and increased lipid peroxidation.

Vision Problems

Vitamin E deficiency may also lead to vision problems. One of the symptoms is retinal thinning or degeneration, where the inner lining of the eye is damaged and begins to become thinner. People with an vitamin E deficiency may also experience blurred vision and difficulty seeing at night.

So, in order to maintain a healthy level of vitamin E within the body, one must take the right dose of this vital nutrient each day. It should be noted, however, that complications can arise from an overdose of vitamin E as well.

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Premenstrual Syndrome and Vitamins Deficiency

Premenstrual Syndrome (or PMS) is a state caused by a number of hormonal imbalances that trigger multiple disruptive symptoms in a high number of women prior to menstruation. Statistic has shown that among 40 million of those who suffer with PMS symptoms, over 5 million need medical treatment.

Most of the time symptoms of PMS symptoms disappear when menstruation starts. Women stay symptom free until 5 to 14 days before the next menstrual period. These regularly happening symptoms after ovulation until menstruation are called Premenstrual syndrome (or PMS). Symptoms diverge from mild to severe enough that they interfere with work and social activities.

PMS may be manifested by a wide range of signs and symptoms:

  • Depression, irritability, tension, fatigue, anxiety
  • Headaches, dizziness and even fainting
  • Acne, hives, boils
  • Joint and back pain
  • Allergy and asthma like signs, hoarseness, sinusitis, sore throat.
  • Bladder infections
  • Food cravings, bloating
  • Tenderness and swelling of the breasts

The most severe form of PMS is called premenstrual dysphoric disorder (PMDD). This disorder takes place in 2 to 9 percent of menstruating women. Symptoms of PMDD and PMS are alike but are much more severe in PMDD.

The etiology of PMS and PMDD is fully unstated. There are hormonal imbalances as well as biochemical neurotransmitters imbalances in the brain which contribute to these.

Various vitamins and minerals have been found helpful in lessening the severity of the symptoms of PMS.

In most cases Calcium with Vitamin D reduce an intensity of PMS symptoms by 48%.

Magnesium deficiency also can significantly worsen PMS symptoms. A double-blind randomized study found oral Magnesium supplementation effective in reducing symptoms of PMS.

Researches from Baylor College in Texas have found that in patients suffering from PMS the level of Zinc in the luteal phase was lower than normal, while the copper level was elevated.

Vitamin B6 (pyridoxine) in the doses of 100 mg was may be helpful in alleviating symptoms of premenstrual syndrome and premenstrual depression.

The study found that Chasteberry, an extract of chaste tree fruit, is helpful for PMS symptoms, especially breast tenderness. Chasteberry support healthy serotonin level in the brain, therefore helping in mental and physical relaxation.

Ginkgo biloba extract in the amount of 160 Mg was also benefits for alleviate symptoms of fluid retention, breast tenderness and anxiety associated with PMS.

Vitamin E in the amount of 400 IU a day given for 3 months can to be effective in alleviating the symptoms of PMS.

Theanine, an amino acid relieves the symptoms of PMS by its normalizing effect on brain neurotransmitters and brain electrical activity.

Theanine is present in Green Tea, and is also available as a nutritional supplement.

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Hemorrhoid Treatment for People with Diabetes

Medical Author: Ruchi Mathur, MD, FRCP(C)
Medical Editors: Jay W. Marks, MD

Some medications used to treat hemorrhoids can have negative effects on blood glucose levels, and thus, may cause physical problems for individuals
with diabetes who are taking diabetes medications. There are options for
patients with diabetes, who also suffer from painful hemorrhoids.

Some simple treatments for hemorrhoids in patients with
diabetes are as follows:

  • Eat plenty of high-fiber foods including bran, fresh fruits and vegetables. Psyllium-containing products also may be used to add fiber to the diet.
  • Avoid straining during defecation or sitting on the toilet for a prolonged period of time. In general, do not sit for prolonged periods of time. Ice compresses may ease the swelling.

Read more on safe hemorrhoid treatments for people with diabetes »

Hemorrhoid Overview

Hemorrhoids are enlarged veins located in the lower part of the rectum and the anus. They become swollen because of increased pressure within them, usually due to straining at stools and during pregnancy because of the pressure of the enlarged uterus.

Internal hemorrhoids are located in the inside lining of the rectum and cannot be felt. They are usually painless and make their presence known by causing bleeding with a bowel movement. Internal hemorrhoids can prolapsed or protrude through the anus.

External hemorrhoids are located underneath the skin that surrounds the anus. They can be felt when they swell and may cause itching or pain with a bowel movement, as well as bleeding. A thrombosed external hemorrhoid occurs when blood within the vein clots, and can cause significant pain.

Picture of hemorrhoids

Hemorrhoid Causes

Hemorrhoids are associated with constipation and straining at bowel movements. Pregnancy is also associated with hemorrhoids. These conditions lead to increased pressure within the hemorrhoidal veins causing them to swell.

Other conditions, for example chronic liver disease, may also cause increased venous pressure and may be associated with hemorrhoid formation. Hemorrhoids are very common and are estimated to occur in up to one-half of the population by age 50.

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Vitamins and depression

Sad Woman

Image by Cmic Blog via Flickr

What is the relationship between the Vitamins and Depression? Vitamins are the vital ingredients in our body. There are a variety of vitamin deficiencies that can lead to depression symptoms. It is applicable to your mental health also.

Vitamins can help to fight depression as well because vitamins regulate hormone production in our body. The hormone in turn keeps us emotionally and physically healthy.

Vitamins deficiency leads to sleeplessness, tiredness, confused state of mind and finally into depression.

Vitamin B complex

Vitamin B1 (thiamine): The brain uses this vitamin to help convert glucose, or blood sugar, into fuel, and without it the brain rapidly runs out of energy. This can lead to fatigue, depression, irritability, anxiety, and even thoughts of suicide. Deficiencies can also cause memory problems, loss of appetite, insomnia, and gastrointestinal disorders. The consumption of refined carbohydrates, such as simple sugars, drains the body’s B1 supply.

Vitamin B3 (niacin)
Pellagra-which produces psychosis and dementia, among other symptoms-was eventually found to be caused by niacin deficiency. Many commercial food products now contain niacin, and pellagra has virtually disappeared. However, subclinical deficiencies of vitamin B3 can produce agitation and anxiety, as well as mental and physical slowness.

Vitamin B5 (pantothenic acid)

Symptoms of deficiency are fatigue, chronic stress, and depression. Vitamin B5 is needed for hormone formation and the uptake of amino acids and the brain chemical acetylcholine, which combine to prevent certain types of depression.
Vitamin B6 (pyridoxine)
This vitamin aids in the processing of amino acids, which are the building blocks of all proteins and some hormones. It is needed in the manufacture of serotonin, melatonin and dopamine. Vitamin B6 deficiencies, although very rare, cause impaired immunity, skin lesions, and mental confusion. A marginal deficiency sometimes occurs in alcoholics, patients with kidney failure, and women using oral contraceptives. MAOIs, ironically, may also lead to a shortage of this vitamin. Many nutritionally oriented doctors believe that most diets do not provide optimal amounts of this vitamin.
Vitamin B12
Because vitamin B12 is important to red blood cell formation, deficiency leads to an oxygen-transport problem known as pernicious anemia. This disorder can cause mood swings, paranoia, irritability, confusion, dementia, hallucinations, or mania, eventually followed by appetite loss, dizziness, weakness, shortage of breath, heart palpitations, diarrhea, and tingling sensations in the extremities. Deficiencies take a long time to develop, since the body stores a three- to five-year supply in the liver. When shortages do occur, they are often due to a lack of intrinsic factor, an enzyme that allows vitamin B12 to be absorbed in the intestinal tract. Since intrinsic factor diminishes with age, older people are more prone to B12 deficiencies.

Folic acid
This B vitamin is needed for DNA synthesis. It is also necessary for the production of SAM (S-adenosyl methionine). Poor dietary habits contribute to folic acid deficiencies, as do illness, alcoholism, and various drugs, including aspirin, birth control pills, barbiturates, and anticonvulsants. It is usually administered along with vitamin B12, since a B12 deficiency can mask a folic acid deficiency. Pregnant women are often advised to take this vitamin to prevent neural tube defects in the developing fetus.

Vitamin C

Subclinical deficiencies can produce depression, which requires the use of supplements. Supplementation is particularly important if you have had surgery or an inflammatory disease. Stress, pregnancy, and lactation also increase the body’s need for vitamin C, while aspirin, tetracycline, and birth control pills can deplete the body’s supply.

Article source

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Vitamins benefit for varicose veins treatment

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Image via Wikipedia

The incidence of varicose veins is higher in developed countries due to lifestyle factors: poor diet (low fibre), lack of activity, and obesity.
Varicose veins have an estimated prevalence of between 5 to 30 percent in the adult population, with women three times more likely to develop varicose veins than men.

Vitamin A
Vitamin A plays a role in several functions throughout the body including vision, immune function, embryonic development and reproduction, bone metabolism, and most important in regards to varicose veins treatment, skin health and antioxidant activity.

B Vitamins
Vitamins B are important for varicose veins treatment as they help maintain strong blood vessels. It has been found that Vitamin B support and increase the rate of metabolism, help maintain healthy skin and muscle tone, enhance immune and nervous system function, and promote cell growth and division-including that of the red blood cells that help prevent anemia.

Vitamin C & Flavonoids
Vitamin C and flavonoids has been found to aid circulation, promote healing of sores, and assist in the strengthening of fragile vein walls during varicose veins treatment.

Vitamin E
Vitamin E helps improve circulation, connective tissue growth and is believed to help relieve calf pain due to narrowing of the arteries.

Vitamin K
The study, published in the Journal of Vascular Research, indicates that inadequate levels of vitamin K may reduce the activity of the matrix GLA protein (MGP) to reduce vascular proliferation and mineralisation, thereby stopping the development of varicosis.

Vitamin P is often used to treat sports injuries, especially in the legs, as they reduce the pain and lessen the effects of prolonged bleeding as well as protecting against antibacterial infections as they are very powerful in maintaining proper levels of blood circulation, one of the causes of varicose veins.

Varicose veins treatment also includes exercise regularly; intake more antioxidant-rich foods; don’t smoke, wearing compression stockings.
For best result in Varicose veins treatment consider a supplement of diosmin, horse chestnut, or pine bark.

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Good and bad cholesterol

Cholesterol is a fatty substance produced in our body and found in certain foods that we eat.
Practically everyone knows that cholesterol can be responsible for arteriosclerosis, heart attacks, a variety of illnesses, but very few are aware of the ways that it is essential to health.

Like everything else, there’s a good and bad side to cholesterol.
At least two-thirds of your body cholesterol is produced by the liver or in the intestine. It is found there as well as in the brain, the adrenals, and nerve fiber sheaths. And when it’s good, it’s very, very good:

  • Cholesterol in the skin is converted to essential vitamin D by the sun’s ultraviolet rays.
  • Cholesterol assists in the metabolism of carbohydrates. The more carbohydrates ingested, the more cholesterol produced.
  • Cholesterol is a prime supplier of life-essential adrenal steroid hormones, such as cortisone.
  • Cholesterol is a component of every membrane and necessary for the production of male and female sex hormones.

Differences in the behavior of cholesterol depend upon the protein to which it is bound. Lipoproteins are the factors in our blood which transport cholesterol.

Low-density lipoproteins (LDL) carry about 65 percent of blood cholesterol and are the bad guys who deposit it in the arteries where, joined by other substances, it becomes artery-blocking plaque.

Very-low-density lipoproteins (VLDL) carry only about 15 percent of blood cholesterol but are the substances the liver needs and uses to produce LDL.

High-density lipoproteins (HDL) carry about 20 percent of blood cholesterol and, composed principally of lecithin, are the good guys whose detergent action breaks up plaque and can transport cholesterol through the blood without clogging arteries.

A recent study found that people with big hips and trim waists have higher HDL cholesterol levels than do those with potbellies, which might explain why females, on the average, live eight years longer than males.

The higher your HDL the lower your chances of developing heart disease.
To increase HDL and decrease LDL in your body you can follow things:

  • Include foods and oils high in HDL in your diet. It will help to decrease LDL levels in your body.
  • Avoid the amount of saturated fats in your diet. In fact, no more than ten percent of your daily calories should be saturated fats. Reducing your daily intake of meat might be a good place to start.
  • Eating five ½ cup servings a day of fresh fruits and vegetables will help.
  • Increase consumption of omega-3 fatty acids found in fish, and green vegetables in your diet. They raise HDL levels in the body.
  • Avoid refined carbohydrates like sugar and refined flours. They raise unhealthy blood cholesterol levels in the body.
  • Do exercise every day. Even going for a walk and increasing your heart rate for 15 minutes a day will help to boost your HDL levels.

It is difficult to make major lifestyle and dietary changes overnight. However, trying to implement some of these suggestions will greatly reduce your risk for heart disease. And living without the fear of a heart disease will allow you to enjoy life all the more.

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Vitamins and Sex

The important thing to remember is that if you’re not feeling up to par, your sex drive is going to suffer along with the rest of you. But very important is also if you want a higher sex drive you need to feed your body the right fuel. Right vitamins, minerals and other nutrients taking as supplements increase your libido dramatically.

Vitamins and mineral essential for libido

Vitamin A deficiency is the most common in impotent. This is a vital vitamin and helps regulate the synthesis of the sex hormone progesterone.

Thiamin (Vitamin B1)
is essential for optimal nerve transmission and energy production throughout the body and of course this means it’s essential for maintaining sex drive.

Vitamin C
is not only a great immune boosting vitamin and needed to stop scurvy, it is also critical in the synthesis of many different sex hormone including androgen, estrogen and progesterone within your adrenal glands.

Vitamin E. There have been many claims for vitamin E in relation to sex. Studies have indeed shown that it increases the fertility in males and females and helps restore male potency.

Selenium is vital for peak sexual performance. Around 50% of the selenium in a man is in the testes and seminal ducts and men lose selenium in their semen.

Zinc is required for the production of testosterone and zinc content of the prostate gland and sperm is higher than in any other art of the body. The largest percentage of zinc in a man’s body is found in the prostate, and a lack of the mineral can produce testicular atrophy and prostate trouble.
A deficiency of zinc is associated with numerous sexual problems, including sperm abnormalities and prostate disease. Zinc not only assists testosterone production it also helps to maintain semen volume and adequate levels of testosterone.

Magnesium is important for the production of sex hormones, such as androgen and estrogen and neurotransmitters that modulate the sex drive with the chemicals dopamine and norepinephrine.
If you want to get even more nutrients to help your sex drive then add in some tried and tested herbs which are known to increase libido.
Remember, vitamins that keep up your energy levels will also do a lot for your sexual performance.

Foods, Herbs, and Supplements for Enhancing Sex

If you want to boost your libido or just add spice to your nightly love life, incorporate some of the following into your daily diet:

Asparagus Ginseng
Avena sativa
Kava kava
Pine nuts
Brewer’s yeast
Shiitake mushrooms
Soy foods
Wheat germ
Fertilized chicken eggs
Whole grains
Ginkgo biloba

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Linkage between vitamin B12 and depression

Some studies have reported of the  relationship between low levels of vitamin B12 and depression.

Depression is a disorder that affects your mood, thoughts, feelings, and behaviour. It is the most common psychiatric ailment in modern society.

Vitamin B12 and other B vitamins, such as folate, play a role in the production of certain brain chemicals that are important in regulating mood and other brain functions.

However, it’s less clear whether vitamin B12 deficiency may be the cause or the result of depression. Poor nutrition is one cause of vitamin B12 deficiency.

B-vitamins (such as B12 and folic acid) may be deficient in those with depression. Folic acid works with SAM (s-adenosylmethionine) to boost neurotransmitter levels.
But poor nutrition may also be a consequence of depression. People who are depressed may lose interest in eating or make less healthy food choices, which may lead to vitamin B12 deficiency.

When you’re depressed, it’s important to try to eat a healthy, balanced diet that includes sources of essential nutrients, including B vitamins.

What is natural good sources of Vitamin B12

Vitamin B12 is plentiful in animal products such as fish, meat, poultry, eggs and milk. Fortified breakfast cereals also are a good source of B12 and other B vitamins.

Especially if you’re older than 50 or you’re a vegetarian, taking a daily supplement that includes vitamin B-12 and other B vitamins may be helpful in making sure your body is getting the nutrients it needs. Talk to your doctor about whether to take a vitamin supplement.

When talking to your doctor about depression, keep in mind that it’s important for him or her to address any underlying physical conditions that might play a part in your depression.

Examples include vitamin deficiency, thyroid disease and certain types of anemia.

Treating these underlying conditions may improve your mood. If you’re still depressed after successful treatment of the underlying condition, your doctor may recommend treatments for depression which include antidepressants and psychological counseling.

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Vitamins help female yeast infection treatment

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Yeast infections usually caused by fungus called Candida albicans. They can occur on the skin, under nails or mucous membranes of the mouth, vagina, bronchi, and lungs. Any yeast infection demands start treatment as soon as possible. According to one study, yeast infections are three times more common in women.

Vitamin and mineral supplement is useful for yeast infection treatment as it can take to restore the body’s immune and digestive system.

Vitamin A as immunity-boosting nutrient

Vitamin A can be used in two ways for women yeast infection treatment. Take vitamin A supplements of 25,000 international units a day, an amount that is five times the daily value and that should be taken only under medical supervision. Vitamin A gelatin capsule can be used as a suppository.

Vitamin C also support of immune system

Vitamin C is essential while Candida treatment to support immune function. Some studies reported benefit of vitamin C vaginal tablets for vaginitis. Vitamin C supplement is taken vaginally or 1,000 mg orally daily.

Vitamin E for itching relief

For female yeast infection treatment Vitamin E used can be taken orally or vaginally. It helps relieve itching and irritation and soothe the delicate vaginal tissue.


When it comes to treatment of yeast infection, the mineral zinc is often a heavyweight contender. It stimulates the production of T lymphocytes, the cells in your immune system that are responsible for cleaning up cells that have been invaded by infection. According to medical research, this makes zinc a best-fighter against Candida albicans.

If you’ve never had a yeast infection before, be sure to see a doctor for proper diagnosis before starting treatment on your own.

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